Trypanosoma cruzi: effects of infection on cathepsin D activity in the midgut of Rhodnius prolixus.
Exp Parasitol
; 112(2): 130-3, 2006 Feb.
Article
em En
| MEDLINE
| ID: mdl-16288741
Cathepsin D activity was estimated in midgut homogenates from Rhodnius prolixus, uninfected and experimentally infected with Trypanosoma cruzi, at different times after blood ingestion. No enzyme activity was found in the anterior midgut and rectum. In the posterior midgut, enzyme activity was found both in lumen and wall. In starved uninfected insects, in lumen and wall, cathepsin D activity was high, decreasing to a constant rate at 1-15 days after feeding. In insects infected with T. cruzi cathepsin D activity increased 1 and 3 days after blood meal. We suggest that these changes in cathepsin D activity in R. prolixus posterior midgut are due to the establishment of T. cruzi infection.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rhodnius
/
Trypanosoma cruzi
/
Catepsina D
/
Insetos Vetores
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Exp Parasitol
Ano de publicação:
2006
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Estados Unidos