Determinants of serum lipoprotein(a) concentration in normolipidaemic individuals without clinical atherosclerosis.
Ann Clin Biochem
; 42(Pt 5): 398-9, 2005 Sep.
Article
em En
| MEDLINE
| ID: mdl-16168197
BACKGROUND: Lipoprotein(a) (Lp(a)) is an independent risk factor for coronary artery diseases. The main objective of this work was to evaluate the determinants of plasma Lp(a) concentrations in normolipidaemic individuals. METHODS: Immunonephelometric quantification of Lp(a) was made in 177 volunteers. A multivariate analysis was employed to verify the influence of clinical and biochemical parameters on plasma Lp(a) concentration. RESULTS: The serum Lp(a) concentration in this population ranged from 0.7 to 40 nmol/L. The Lp(a) predictors were: sex (female), HDL2 triglyceride (negative) and LDL-cholesterol (positive). CONCLUSIONS: The modulation of plasma Lp(a) concentration in this study points to pro-atherogenic lipoprotein associations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Arteriosclerose
/
Lipoproteína(a)
/
Lipídeos
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Ann Clin Biochem
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Reino Unido