[Effects of lobectomy on the auditory mid-latency response in temporal lobe epileptic patients]. / Efectos de la lobectomía sobre el potencial evocado auditivo de latencia media en pacientes con epilepsia del lóbulo temporal.
Rev Neurol
; 41(2): 81-5, 2005.
Article
em Es
| MEDLINE
| ID: mdl-16028185
AIM: Auditory mid-latency response (MLR) has been studied in temporal lobe epileptic patients in order to evaluate the relationship between the different components of this evoked response and their probable generators in the most rostral part of auditory pathway. PATIENTS AND METHODS: MLR was studied in eight patients with temporal lobe epilepsy before lobectomy, and 1, 6 and 12 months after the surgical treatment, and eight healthy subjects matched for age and gender. Recording electrodes were placed in Cz, T3 and T4 according to the international 10-20 system. Comparisons were carried out in terms of peak to peak amplitude, latency and interpeak intervals of the main components (Mann-Whitney U test, Wilcoxon test). RESULTS: Epileptic patients showed statistically significant prolonged latency of all components, and increased Pa-Pb interpeak interval duration respect to control group. No significant variations were found in the amplitude of the studied components. There were no differences between left and right lobotomized patients. However, a marked tendency to the shortening of latency was observed in the left group after the surgical treatment. CONCLUSIONS: The differences between the pre-surgical records of patients and controls reflect an impaired activity in the generating areas for MLR components. There appears to be a trend to a different behaviour after right or left lobectomy, probably related to the extension of the removed tissue.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Epilepsia do Lobo Temporal
/
Potenciais Evocados Auditivos
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Rev Neurol
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Cuba
País de publicação:
Espanha