[Oral clarithromycin as a treatment option in chronic post-operative endophthalmitis]. / Claritromicina oral como opción terapéutica en endoftalmitis post-quirúrgicas tardías.
Arch Soc Esp Oftalmol
; 80(6): 339-44, 2005 Jun.
Article
em Es
| MEDLINE
| ID: mdl-15986274
PURPOSE: To assess the outcome of medical treatment with oral clarithromycin in patients with chronic post-surgical endophthalmitis. METHODS: This prospective study was performed between January 1999 and September 2003. Patients with a diagnosis of chronic post-surgical endophthalmitis of bacterial etiology were included. All received 500 mg of oral clarithromycin twice a day for 14 days. The initial and final visual acuity, etiology, post-surgical time of presentation, treatment-delay time, and follow up were recorded. According to the treatment results, patients were distributed into 3 separate groups: 1) complete response, 2) partial response, 3) no response. Data from these groups were compared by means of the Student's t test and Fisher exact test, depending on which was considered most suitable. RESULTS: Fifteen cases of chronic endophthalmitis (11 of Propionibacterium acnes, 4 of Staphylococcus epidermidis) were diagnosed. A complete response was observed in 4 cases, partial response in 4 cases, and no response in 7 cases. Final visual acuity greater than 0.5 was significantly more likely in the complete response group when compared with the no response group (Fisher exact test = 0.0454, p=0.05), however, the same comparison between the complete response group and the partial response group was not significant. CONCLUSION: Medical treatment with oral clarithromycin could be useful in some patients with chronic post-surgical endophthalmitis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Propionibacterium acnes
/
Infecções Estafilocócicas
/
Staphylococcus epidermidis
/
Infecção da Ferida Cirúrgica
/
Endoftalmite
/
Infecções Relacionadas à Prótese
/
Infecções por Bactérias Gram-Positivas
/
Claritromicina
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Aged80
Idioma:
Es
Revista:
Arch Soc Esp Oftalmol
Ano de publicação:
2005
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Espanha