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[Subcutaneous phaeohyphomycosis due to Exophiala spinifera in a renal transplant recipient]. / Phaéohyphomycose sous-cutanée à Exophiala spinifera chez une malade greffée rénale.
Dutriaux, C; Saint-Cyr, I; Desbois, N; Calès-Quist, D; Diedhou, A; Boisseau-Garsaud, A-M.
Afiliação
  • Dutriaux C; Service de Dermatologie, CHU de Fort-de-France, Martinique.
Ann Dermatol Venereol ; 132(3): 259-62, 2005 Mar.
Article em Fr | MEDLINE | ID: mdl-15924051
INTRODUCTION: Among the dematiaceous fungi responsible for human or animal phaeohyphomycosis, the Exophiala genus is a well-known etiologic agent and presently includes nine species considered as opportunist pathogens. To our knowledge, Exophiala spinifera has been reported as causative agent of only thirteen cases of cutaneous or systemic phaeohyphomycosis. We describe some typical phaeohyphomycotic cysts. CASE-REPORT: A 59 year-old female renal transplant recipient, treated with ciclosporine and prednisone, presented with two painless nodular and suppurative lesions of the leg, extending slowly. Histological and microbiological examinations identified Exophiala spinifera. The patient's condition improved with voriconazole treatment. DISCUSSION: Phaeohyphomycosis is a rare but cosmopolitan mycosis found throughout the world. Immunocompromised hosts are more vulnerable to these infections and more likely to develop severe and disseminated forms of uncertain outcome. Mycological and histological findings are important to confirm the diagnosis. The prognosis is benign and complete cure is common in cutaneous and superficial forms. Treatment is not well defined, often empirical and usually relies on antifungals and/or complete surgical resection.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Exophiala / Transplante de Rim / Micoses Tipo de estudo: Prognostic_studies Limite: Female / Humans / Middle aged Idioma: Fr Revista: Ann Dermatol Venereol Ano de publicação: 2005 Tipo de documento: Article País de afiliação: Martinica País de publicação: França
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Exophiala / Transplante de Rim / Micoses Tipo de estudo: Prognostic_studies Limite: Female / Humans / Middle aged Idioma: Fr Revista: Ann Dermatol Venereol Ano de publicação: 2005 Tipo de documento: Article País de afiliação: Martinica País de publicação: França