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Comparative study of the efficacy of the topical application of hydrocortisone, therapeutic ultrasound and phonophoresis on the tissue repair process in rat tendons.
Koeke, Paulo Umeno; Parizotto, Nivaldo Antonio; Carrinho, Patrícia Michelassi; Salate, Ana Claúdia Bonone.
Afiliação
  • Koeke PU; Program of Post-Graduation Interunits in Bioengineering, University of São Paulo, São Paulo, Brazil.
Ultrasound Med Biol ; 31(3): 345-50, 2005 Mar.
Article em En | MEDLINE | ID: mdl-15749557
The purpose of this study was to compare the treatment efficacy of topical application of hydrocortisone, therapeutic ultrasound (US) and phonophoresis on the rat's Achilles tendon (tendo calcaneus) repair process after tenotomy. The two treated groups with US were made in a pulsed mode. The irradiation of US was performed at a frequency of 1 MHz and an intensity of 0.5 W/cm2 (SATA), for 5 min each session. The tendons were analyzed using the polarized light microscopy. The results showed that the treated group with the topical application of hydrocortisone has not been delivered transdermally and that the molecule of collagen responds to the ultrasonic stimulation. The treatment with phonophoresis was the more efficient method. These findings allow us to conclude that the US stimulates the acceleration of tissue repair processes and induces the transdermal delivery of hydrocortisone in a therapeutic concentration on the tendon.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tendão do Calcâneo / Terapia por Ultrassom / Cicatrização / Hidrocortisona / Fonoforese / Anti-Inflamatórios Limite: Animals Idioma: En Revista: Ultrasound Med Biol Ano de publicação: 2005 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tendão do Calcâneo / Terapia por Ultrassom / Cicatrização / Hidrocortisona / Fonoforese / Anti-Inflamatórios Limite: Animals Idioma: En Revista: Ultrasound Med Biol Ano de publicação: 2005 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido