Your browser doesn't support javascript.
loading
Chronic Histoplasma capsulatum infection of the central nervous system successfully treated with fluconazole.
Tiraboschi, I; Casas Parera, I; Pikielny, R; Scattini, G; Micheli, F.
Afiliação
  • Tiraboschi I; Department of Infectious Diseases, Hospital de Clinicas Jose de San Martin, Buenos Aires, Argentina.
Eur Neurol ; 32(2): 70-3, 1992.
Article em En | MEDLINE | ID: mdl-1563464
A 48-year-old man with a long-standing history of communicating hydrocephalus is reported. Ventriculoperitoneal shunting led to clinical improvement, but symptoms recurred despite surgical re-exploration switching the shunt to an atrial drainage. Ten months after the last surgical procedure, an acute myelopathy developed. Concomitant pharyngeal granuloma examination identified Histoplasma capsulatum (Hc) yeasts. Despite initial response to amphotericin B, Hc was isolated from cerebrospinal fluid (CSF), valve reservoir and distal catheter after two courses of therapy. Fluconazole successfully sterilized CSF, but transverse myelopathy persisted unchanged, and shunting was needed to control hydrocephalus.
Assuntos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fluconazol / Meningite Fúngica / Histoplasmose Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Eur Neurol Ano de publicação: 1992 Tipo de documento: Article País de afiliação: Argentina País de publicação: Suíça
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fluconazol / Meningite Fúngica / Histoplasmose Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Eur Neurol Ano de publicação: 1992 Tipo de documento: Article País de afiliação: Argentina País de publicação: Suíça