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Acute hemorrhagic leukoencephalitis mimicking herpes simplex encephalitis: case report.
Martins, Henrique Milhomem; Teixeira, Antônio Lúcio; Lana-Peixoto, Marco Aurélio.
Afiliação
  • Martins HM; Minas Gerais Center for Investigation of Multiple Sclerosis, Medical School, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
Arq Neuropsiquiatr ; 62(1): 139-43, 2004 Mar.
Article em En | MEDLINE | ID: mdl-15122448
Acute hemorrhagic leukoencephalitis (AHLE) is a more severe form of acute disseminated encephalomyelitis (ADEM) characterized by a fulminant clinical course and the presence of hemorrhagic necrosis of the white matter. We report the case of a 57-year-old woman who developed delirium following a respiratory infection. Magnetic resonance imaging of the brain disclosed signal abnormalities in the frontal and temporal lobes, usually found in herpes simplex encephalitis (HSE). Gram stain, India ink and acid-fast bacilli staining were all negative in CSF as was a polymerase chain reaction (PCR) for herpes simplex virus. A diagnosis of AHLE was made and the patient was treated with i.v. methylprednisolone 1g/day for 5 days. Despite treatment, the patient developed several neurological sequelae compatible with the severity of her illness.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucoencefalite Hemorrágica Aguda / Encefalite por Herpes Simples Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: Arq Neuropsiquiatr Ano de publicação: 2004 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucoencefalite Hemorrágica Aguda / Encefalite por Herpes Simples Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Middle aged Idioma: En Revista: Arq Neuropsiquiatr Ano de publicação: 2004 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha