Serum reproductive hormone levels and sperm production in male adult rats after treatment with arresting, a fraction obtained from seminiferous tubules conditioned medium.
Andrologia
; 35(6): 351-7, 2003 Dec.
Article
em En
| MEDLINE
| ID: mdl-15018137
This study used seminiferous tubule (ST) segments from adult rats to condition culture medium that had been concentrated, size fractioned and administered 10-84 days to adult rats by subcutaneous or intratesticular injection and the effects on testes weight, testosterone, luteinizing hormone (LH) and FSH levels and (homogenization-resistant) epididymal sperm count were determined. The conditioned medium obtained 2 days after culture of ST was fractionated in a 30-100 kDa component. The fraction was injected subcutaneously or intratesticularly. This factor(s), named arresting, decreases sperm count in the epididymis from 13 days to 84 days of treatment without changes in serum LH or testosterone levels. The results of the present study suggest that arresting acts on spermiogenesis/spermiation and/or the entry of sperm into the epididymis from the efferent ductules.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Túbulos Seminíferos
/
Espermatozoides
/
Hormônio Luteinizante
/
Proteínas de Plasma Seminal
/
Hormônio Foliculoestimulante
Limite:
Animals
Idioma:
En
Revista:
Andrologia
Ano de publicação:
2003
Tipo de documento:
Article
País de afiliação:
Chile
País de publicação:
Alemanha