Investigation of the importance of the C-2 oxygen function in the transformation of stemodin analogues by Rhizopus oryzae ATCC 11145.
Phytochemistry
; 65(6): 701-10, 2004 Mar.
Article
em En
| MEDLINE
| ID: mdl-15016566
A new stemodinoside, stemodin-alpha-L-arabinofuranoside (5), was isolated from the plant Stemodia maritima. Incubation of stemodin (2) with Rhizopus oryzae ATCC 11145 gave 2 alpha,7 beta,13(S)-trihydroxystemodane (17) and 2 alpha,3 beta,13(S),16 alpha-tetrahydroxystemodane (18) whilst stemodinone (8) afforded 6 alpha,13(S)-dihydroxystemodan-2-one (19). The bioconversion of 2 beta,13(S)-dihydroxystemodane (10) by the fungus yielded 2 beta,7 beta,13(S)-trihydroxystemodane (20) whereas stemod-12-en-2-one (9) provided 7 beta,17-dihydroxystemod-12-en-2-one (21). The results provide useful information about the relationship between the functional groups of the substrates and their potential for bioconversion.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Rhizopus
/
Diterpenos
Idioma:
En
Revista:
Phytochemistry
Ano de publicação:
2004
Tipo de documento:
Article
País de afiliação:
Jamaica
País de publicação:
Reino Unido