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Clonazepam in the pharmacological treatment of vertigo and tinnitus.
Ganança, Mauricio Malavasi; Caovilla, Heloisa Helena; Ganança, Fernando Freitas; Ganança, Cristina Freitas; Munhoz, Mário Sérgio Lei; da Silva, Maria Leonor Garcia; Serafini, Flávio.
Afiliação
  • Ganança MM; Division of Neurootology, Department of Otorhinolaryngology and Communicative Disorders, Universidade Federal de São Paulo-Escola Paulista de Medicina, São Paulo, Brazil. mauricio.gananca@globo.com
Int Tinnitus J ; 8(1): 50-3, 2002.
Article em En | MEDLINE | ID: mdl-14763236
We carried out a retrospective survey of 25 years of clinical experience with the use of clonazepam as a vestibular and tinnitus suppressant in the pharmacological treatment of vestibular or cochleovestibular disorders due to different causes. We reviewed the medical records of 3,357 outpatients treated with a 0.5 or 1.0-mg daily dosage of oral clonazepam during 60-180 days. Complete or substantial control of vertigo or nonvertiginous dizziness was achieved in 77.4% of the vertigo patients. Tinnitus was improved in 32.0% of the tinnitus patients. Light or mild drowsiness, depression, nightmares, or lowering of libido, reported by 16.9% of the patients as adverse side effects, tended to subside with continued therapy. We concluded that clonazepam is a very useful and safe drug for the symptomatic treatment of patients suffering from cochleovestibular disorders.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zumbido / Vertigem / Clonazepam / Moduladores GABAérgicos Tipo de estudo: Diagnostic_studies / Evaluation_studies / Observational_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int Tinnitus J Assunto da revista: AUDIOLOGIA Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Zumbido / Vertigem / Clonazepam / Moduladores GABAérgicos Tipo de estudo: Diagnostic_studies / Evaluation_studies / Observational_studies Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int Tinnitus J Assunto da revista: AUDIOLOGIA Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos