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Hantavirus pulmonary syndrome, southern Chile.
Riquelme, Raúl; Riquelme, Mauricio; Torres, Antoni; Rioseco, Maria Luisa; Vergara, José Antonio; Scholz, Luis; Carriel, Andrea.
Afiliação
  • Riquelme R; Puerto Montt Regional Hospital, Puerto Montt, Chile. raul@telsur.cl
Emerg Infect Dis ; 9(11): 1438-43, 2003 Nov.
Article em En | MEDLINE | ID: mdl-14718088
We analyzed data from 25 consecutive patients with hantavirus pulmonary syndrome (HPS) admitted to the Puerto Montt and Osorno Regional Hospitals, southern Chile, from 1997 to 2001, emphasizing epidemiologic, clinical, radiographic, treatment, and laboratory aspects. Hemorrhage was frequent (64%), and 48% of patients showed alterations in renal function. Ten patients died (40%). We identified three groups of patients, which included the following: 1) those with the least severe form who had prodromic symptoms without pulmonary involvement; 2) those with moderate illness who had interstitial pulmonary infiltrates, usually needed supplemental nasal oxygen, were hemodynamically stable, and had an APACHE II <12 (none of whom died); and 3) those with the severe form who required mechanical ventilation, frequently had hemodynamic instability (93%), experienced a high mortality rate (77%), and had an APACHE II >12. Mild forms of HPS also exist, which are poorly known; the symptoms could be confounded with those of other viral diseases, leading to underdiagnosis.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Surtos de Doenças / Síndrome Pulmonar por Hantavirus / Doenças Transmissíveis Emergentes Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Chile Idioma: En Revista: Emerg Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2003 Tipo de documento: Article País de afiliação: Chile País de publicação: Estados Unidos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Surtos de Doenças / Síndrome Pulmonar por Hantavirus / Doenças Transmissíveis Emergentes Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Chile Idioma: En Revista: Emerg Infect Dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2003 Tipo de documento: Article País de afiliação: Chile País de publicação: Estados Unidos