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Long-term neurologic consequences of nutritional vitamin B12 deficiency in infants.
Graham, S M; Arvela, O M; Wise, G A.
Afiliação
  • Graham SM; Prince of Wales Children's Hospital, Randwick, Australia.
J Pediatr ; 121(5 Pt 1): 710-4, 1992 Nov.
Article em En | MEDLINE | ID: mdl-1432418
A review of the clinical findings in six infants with nutritional vitamin B12 deficiency seen during the last 10 years was undertaken and an attempt made to obtain long-term neurologic follow-up. There was a consistent clinical pattern in vitamin B12-deficient infants; irritability, anorexia, and failure to thrive were associated with marked developmental regression and poor brain growth. Two of the four patients who qualified for long-term review had a poor intellectual outcome. Although early response to treatment is satisfying, the long-term consequences of nutritional vitamin B12 deficiency in infants emphasize the need for prevention or early recognition of this syndrome.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina B 12 / Doenças do Sistema Nervoso Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child, preschool / Female / Humans / Infant Idioma: En Revista: J Pediatr Ano de publicação: 1992 Tipo de documento: Article País de afiliação: Austrália País de publicação: Estados Unidos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Deficiência de Vitamina B 12 / Doenças do Sistema Nervoso Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child, preschool / Female / Humans / Infant Idioma: En Revista: J Pediatr Ano de publicação: 1992 Tipo de documento: Article País de afiliação: Austrália País de publicação: Estados Unidos