[Hyperthyrotropinemia in Mexican newborns]. / Hipertirotropinemia en recién nacidos mexicanos.
Salud Publica Mex
; 45(4): 269-75, 2003.
Article
em Es
| MEDLINE
| ID: mdl-12974044
OBJECTIVE: To assess the differences in the blood concentration levels of the thyroid stimulating hormone and their possible use as an indicator of iodine sufficiency, in a sample of Mexican newborns. MATERIAL AND METHODS: A cross-sectional study was conducted from September 1999 to August 2000, among 25,427 Mexican newborns in the Ministry of Health clinics from 5 states. A total of 8,095 heel-prick and 17,332 umbilical cord blood samples were analyzed. Blood samples were collected in filter paper and processed by enzyme-linked immunosorbent assay. The Mann-Whitney U test and the Kruskal-Wallis test were used for statistical analyses. RESULTS: Hyperthyrotropinemia was found in 9.95% of heel samples and in 24.27% of umbilical cord samples (TSH > 5 microUl/ml). CONCLUSIONS: The percentage of hyperthyrotropinemia observed in this study was higher than that expected in a population with sufficient iodine intake; these findings could be due to poor maternal iodine intake.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tireotropina
/
Triagem Neonatal
/
Hipotireoidismo
Tipo de estudo:
Clinical_trials
/
Diagnostic_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Newborn
País/Região como assunto:
Mexico
Idioma:
Es
Revista:
Salud Publica Mex
Ano de publicação:
2003
Tipo de documento:
Article
País de publicação:
México