Bone histomorphometry in Cushing's syndrome.

Borelli, A; Leite, M O; Correa, P H; Jorgetti, V; Marcondes, J A; Batalha, J R; Cintra, A B; Wajchenberg, B L

Borelli, A; Leite, M O; Correa, P H; Jorgetti, V; Marcondes, J A; Batalha, J R; Cintra, A B; Wajchenberg, B L.

Afiliação

Borelli A; Endocrine Service, 1st Medical Clinics Hospital das Clínicas, University of São Paulo, Brazil.

J Endocrinol Invest ; 15(11): 783-7, 1992 Dec.

Article em En | MEDLINE | ID: mdl-1291592

RESUMO

Bone involvement is a common finding in Cushing's syndrome. The actions of corticosteroids on bone have been studied quite intensively but only a few studies of bone histomorphometry in this syndrome have been published. In this paper we present histomorphometric measurements of bone activity in 7 patients with a postoperative reevaluation in two. The results show irregular alterations on histomorphometric parameters with an increased bone resorption and decreased bone formation rate. After surgery the abnormalities changed towards normal.

Assuntos

Osso e Ossos/patologia; Síndrome de Cushing/patologia; Adulto; Reabsorção Óssea/patologia; Cálcio/urina; Síndrome de Cushing/sangue; Síndrome de Cushing/cirurgia; Feminino; Hormônios/sangue; Hormônios/urina; Humanos; Ílio/patologia

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osso e Ossos / Síndrome de Cushing Limite: Adult / Female / Humans Idioma: En Revista: J Endocrinol Invest Ano de publicação: 1992 Tipo de documento: Article País de afiliação: Brasil País de publicação: Itália

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