[Estrogen and progesterone receptors in uterine cervix]. / Receptores de estrogeno e progesterona em cervix uterina.
J Bras Ginecol
; 95(9): 411-5, 1985.
Article
em Pt
| MEDLINE
| ID: mdl-12267713
PIP: This report describes the measurement of estrogen (ER) and progesterone receptors (PR) in cytosols of human exocervix and endometrium, using a charcoal dextran method. Endometrial tissues were obtained from patients undergoing hysterectomy. Curettage specimens of exocervix were obtained from healthy women throughout the menstrual cycle, from women taking combined oral contraceptives, and from postmenopausal women. The highest ER and PR concentrations and ER/PR ratio were detected in endometrium. Exocervix ER and PR levels were lower as compared to endometrium (14% and 3.6% respectively) and no cyclic variations were detectable. Specimens of exocervix from women taking oral contraceptives showed a significant PR decrease. In postmenopausal women, cervical ER and PR levels were significantly higher than in premenopausal women. No difference in binding specificity of estradiol and progesterone to their receptors could be found between endometrium and exocervix. The authors concluded that the effect of estrogen and progesterone on the cervix is limited by the low cytoplasmic receptor levels.^ieng
Palavras-chave
Biology; Cervix; Clinical Research; Contraception; Contraceptive Agents, Female; Corpus Luteum Hormones; Endocrine System; Endometrium; Estrogens; Genitalia; Genitalia, Female; Hormones; In Vitro; Menopause; Menstrual Cycle; Menstruation; Oral Contraceptives; Physiology; Progestational Hormones; Progesterone; Reproduction; Research And Development; Urogenital System; Uterus
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Progesterona
/
Sistema Urogenital
/
Útero
/
Colo do Útero
/
Hormônios do Corpo Lúteo
/
Endométrio
/
Estrogênios
/
Genitália
/
Genitália Feminina
/
Hormônios
Idioma:
Pt
Revista:
J Bras Ginecol
Ano de publicação:
1985
Tipo de documento:
Article
País de publicação:
Brasil