Epidemiology of endemic Bartonella bacilliformis: a prospective cohort study in a Peruvian mountain valley community.
J Infect Dis
; 186(7): 983-90, 2002 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-12232839
Bartonella bacilliformis has caused debilitating illness since pre-Incan times, but relatively little is known about its epidemiology. A population-based, prospective cohort investigation was conducted in a Peruvian community with endemic bartonellosis. By use of house-to-house and hospital surveillance methods, cohort participants were monitored for evidence of bartonellosis. Of 690 participants, 0.5% had asymptomatic bacteremia at study initiation. After 2 years of follow-up, the incidence of infection was 12.7/100 person-years. The highest rates were in children <5 years old, and there was a linear decrease in incidence with increasing age. Seventy percent of cases were clustered in 18% of households. Age and bartonellosis in a family member were the best predictors of B. bacilliformis infection. There were multiple clinical presentations and significant subclinical infection. A cost-effective control strategy should include vector control and surveillance efforts focused on children and clusters of households with highest endemicity.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Bartonella
/
Infecções por Bartonella
Tipo de estudo:
Etiology_studies
/
Incidence_studies
/
Observational_studies
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Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Adolescent
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Adult
/
Aged
/
Child
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Child, preschool
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Humans
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Infant
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Male
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Middle aged
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Newborn
País/Região como assunto:
America do sul
/
Peru
Idioma:
En
Revista:
J Infect Dis
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
Estados Unidos
País de publicação:
Estados Unidos