Your browser doesn't support javascript.
loading
Salivary progesterone levels and rate of ovulation are significantly lower in poorer than in better-off urban-dwelling Bolivian women.
Vitzthum, Virginia J; Bentley, Gillian R; Spielvogel, Hilde; Caceres, Esperanza; Thornburg, Jonathan; Jones, Lary; Shore, Sarah; Hodges, Kelly R; Chatterton, Robert T.
Afiliação
  • Vitzthum VJ; Institute for Primary and Preventative Health Care, and Department of Anthropology, Binghamton University (SUNY), Binghamton, NY 13901, USA. vvitzthu@nsf.gov
Hum Reprod ; 17(7): 1906-13, 2002 Jul.
Article em En | MEDLINE | ID: mdl-12093859
BACKGROUND: Agriculturalists in less-developed countries (LDC) have lower progesterone levels than urban industrialized populations. However, it is unknown if urban LDC populations are also relatively lower. We tested whether urban Bolivia samples-poorer (Bol-p) and better-off (Bol-b)-have lower progesterone than a Chicago (USA) sample, and whether progesterone and rate of ovulation are lower in Bol-p than in Bol-b. METHODS: Serial salivary samples collected from Bolivians, screened according to strict exclusion criteria during two complete menstrual cycles, were radioimmunoassayed for progesterone; anthropometrics were collected at mid-follicular and mid-luteal phases. RESULTS: Progesterone levels are lower in the Bolivia samples, and higher in the Bol-b than Bol-p; ovulation rate is greater in Bol-b than Bol-p. For only ovulatory cycles, mean-follicular-P (pmol/l), mean-luteal-P (pmol/l), and mean-peak-P (pmol/l) are respectively 65, 142 and 208 in Bol-p; 76, 167 and 232 in Bol-b; and 96, 240 and 330 in Chicago. Principal components representing body-size and progesterone level are positively correlated (r = 0.404, P = 0.005). CONCLUSIONS: Progesterone levels appear to be influenced by chronic and acute ecological conditions, evidenced by the association with body-size and the probability of ovulation respectively. These findings have implications for understanding cancer aetiology, developing population-appropriate hormonal contraceptives, and modelling the evolution and functioning of the reproductive system.
Assuntos
Buscar no Google
Adicionar na Minha BVS
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ovulação / Pobreza / Progesterona / Saliva / População Urbana Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Limite: Adult / Female / Humans País/Região como assunto: America do sul / Bolivia Idioma: En Revista: Hum Reprod Assunto da revista: MEDICINA REPRODUTIVA Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Buscar no Google
Adicionar na Minha BVS
Imprimir
XML
PubMed Links

Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ovulação / Pobreza / Progesterona / Saliva / População Urbana Tipo de estudo: Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Limite: Adult / Female / Humans País/Região como assunto: America do sul / Bolivia Idioma: En Revista: Hum Reprod Assunto da revista: MEDICINA REPRODUTIVA Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido