Your browser doesn't support javascript.
loading
Incidence and prevalence of human group C rotavirus infections in Argentina.
Castello, Alejandro A; Argüelles, Marcelo H; Villegas, Guillermo A; Olthoff, Alicia; Glikmann, Graciela.
Afiliação
  • Castello AA; Laboratorio de Virología, Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Buenos Aires, Argentina.
J Med Virol ; 67(1): 106-12, 2002 May.
Article em En | MEDLINE | ID: mdl-11920824
The incidence of human group C rotavirus infections among children and adults in Buenos Aires was evaluated by enzyme linked immunosorbent assays (ELISA) based on recombinant group C VP6 protein (Cowden strain). A total of 976 stool samples taken from patients (ages 6 months to 15 years) with acute diarrhea were tested for the presence of group C rotavirus. Among these, only 10 (1.02%) were group C rotavirus positive by enzyme-linked immunosorbent assay (ELISA) confirmed by absorption with group C VP6 antibodies and by RT-PCR for both VP6 and VP7 genes. The average age (5.86 years) was significantly superior to that in group A-infected patients (1.63 years). Previous exposure to this virus was assessed by detecting specific IgG in sera taken from healthy individuals grouped by age. Of 844 sera tested, 425 (50.3%) were group C IgG positive by ELISA, confirmed by Western blot analysis. The rates of IgG positivity for group A and C rotaviruses during the first years of life indicated that infections with group C are frequent in older children (3-5 years), whereas group A infections are prevalent in infants and young children (6-18 months). This study shows that group C rotavirus infections in Argentine children occur later in life than group A and are relatively common in spite of the low detection rate of this virus.
Assuntos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Rotavirus / Proteínas do Capsídeo / Diarreia Tipo de estudo: Incidence_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant País/Região como assunto: America do sul / Argentina Idioma: En Revista: J Med Virol Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos
Buscar no Google
Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Rotavirus / Proteínas do Capsídeo / Diarreia Tipo de estudo: Incidence_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Child, preschool / Humans / Infant País/Região como assunto: America do sul / Argentina Idioma: En Revista: J Med Virol Ano de publicação: 2002 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos