[Chromosome replication in mycobacteria]. / Replicación del cromosoma en micobacterias.
Acta Cient Venez
; 52 Suppl 1: 42-4, 2001.
Article
em Es
| MEDLINE
| ID: mdl-11899705
Variation in growth rate has provided a basis for the broad classification of Mycobacterium: (i) the slow-growing class includes the human pathogens Mycobacterium tuberculosis and M. leprae, and (ii) the fast-growing class includes saprophytic nonpathogens, such as M. smegmatis. An intimate association between DNA chromosomal replication and growth rate have been suggested. However, the molecular basis of this relation is unknown. In this article, we summarise our recent work on the study of the origin replication region of some species of mycobacteria, determination of the factors regulating the initiation of DNA replication and the characterisation of the main factor of the replicative machinery, the DnaA protein.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
DNA Bacteriano
/
Cromossomos Bacterianos
/
Replicação do DNA
/
Mycobacterium
Idioma:
Es
Revista:
Acta Cient Venez
Ano de publicação:
2001
Tipo de documento:
Article
País de publicação:
Venezuela