Conorfamide, a Conus venom peptide belonging to the RFamide family of neuropeptides.
Toxicon
; 40(4): 401-7, 2002 Apr.
Article
em En
| MEDLINE
| ID: mdl-11738233
A novel Conus peptide, conorfamide-Sr1, has been characterized. The sequence of the natural peptide was determined using standard Edman sequencing methods and mass spectrometry, and confirmed by chemical synthesis. The peptide has 12 amino acids and no cysteine residues. The following sequence was obtained: GPMGWVPVFYRF-NH(2). No other peptide from a vermivorous Atlantic Conus species has previously been characterized. Conorfamide-Sr1 belongs to the RFamide neuropeptide family, and is the first RFamide peptide to be found in any venom. The presence of conorfamide-Sr1 as a major peptide in Conus spurius venom suggests that Conus lineages in the Atlantic may have evolved novel Conus venom peptide families.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peptídeos
/
Venenos de Moluscos
Limite:
Animals
Idioma:
En
Revista:
Toxicon
Ano de publicação:
2002
Tipo de documento:
Article
País de afiliação:
México
País de publicação:
Reino Unido