Na+/Li+ exchange kinetic characterization. Red blood cells from normotensive individuals.

Corchs, J L; Taborda, D; Mujica, G; Serrani, R E

Corchs, J L; Taborda, D; Mujica, G; Serrani, R E.

Afiliação

Corchs JL; Department of Physiology, School of Medicine, National University of Rosario, Santa Fe, Argentina. gmujica@citynet.net.ar

Acta Physiol Pharmacol Bulg ; 25(3-4): 75-9, 2000.

Article em En | MEDLINE | ID: mdl-11688550

RESUMO

The plasma membrane Na+/Li+ exchange is of research interest because it is involved in some pathologic states. A kinetic analysis of this transport system would be of greater importance as compared to the flux determination under "standard" conditions (reactants saturating levels) as a way to define normal values. Unidirectional lithium fluxes in red blood cells from normal adults were determined as a function of "trans" (contralateral) sodium ion concentration. Relating Li+ efflux and influx (Na+ "trans") kinetic parameters we found free carrier reorientation between the two phases (asymmetry).

Assuntos

Eritrócitos/metabolismo; Lítio/metabolismo; Sódio/metabolismo; Cátions Monovalentes; Células Cultivadas; Humanos; Transporte de Íons; Cinética; Potássio/metabolismo; Espectrofotometria Atômica

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sódio / Eritrócitos / Lítio Limite: Humans Idioma: En Revista: Acta Physiol Pharmacol Bulg Ano de publicação: 2000 Tipo de documento: Article País de afiliação: Argentina País de publicação: Bulgária

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