An investigation of recurrent pine oil poisoning in an infant by the use of gas chromatographic-mass spectrometric methods.
J Pediatr
; 87(1): 115-8, 1975 Jul.
Article
em En
| MEDLINE
| ID: mdl-1151533
An 18-month-old infant required six hospital admissions in a period of six months for episodes consisting of coughing, respiratory depression, hematemesis, coma, dehydration, and lesions about the mouth. A negative history of ingestion of toxins was repeatedly obtained from the family and two home inspection by the local Health Department failed to identify potential toxins. Metabolic work-up was entirely negative. Utilizing methods of GC-MS, metabolites of a-terpineol were isolated from infant urine on two admissions to the hospital. These metabolites were confirmed by mass spectrometry to be the same metabolites excreted by Sprague-Dawley rats injected with a-terpineol or pine oil. The child had no additional episodes after physical separation from the home environment.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Silício
/
Terpenos
/
Compostos de Trimetilsilil
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
/
Infant
/
Male
Idioma:
En
Revista:
J Pediatr
Ano de publicação:
1975
Tipo de documento:
Article
País de publicação:
Estados Unidos