Frequency of Mycoplasma hominis and Ureaplasma urealyticum infections in women with systemic lupus erythematosus.
Rev Soc Bras Med Trop
; 34(3): 243-7, 2001.
Article
em En
| MEDLINE
| ID: mdl-11460209
Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) have been detected in the urine of women with systemic lupus erythematosus (SLE). We evaluated the presence of these mycoplasma in the endocervix of women presenting SLE. A total of 40 SLE patients (mean age 40.2 years), and 51 healthy women (mean age 30.9 years), were studied. Endocervical swabs were cultured in specific liquid media for MH or UU, detected by a quantitative color assay, and considered positive at >10(3) dilutions. Statistical analysis was performed using the two-tailed Fisher test. UU was detected in 52.5 % of patients and in 11.8% of controls (p= 0.000059). MH was detected in 20% of patients and 2% controls (p=0.003905). Both mycoplasmas were detected in 7.3% patients and 0% controls (p<0.000001). The results reported here corroborate the association of the mycoplasma infection and SLE. Thus, these agents may stimulate the production of autoreactive clones.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ureaplasma urealyticum
/
Infecções por Ureaplasma
/
Mycoplasma hominis
/
Lúpus Eritematoso Sistêmico
/
Infecções por Mycoplasma
Limite:
Adult
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Female
/
Humans
Idioma:
En
Revista:
Rev Soc Bras Med Trop
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil