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[Importance of the bacterium-host interaction in coagulase-negative staphylococci isolated from neonates]. / Importancia de la relación huésped-parásito en estafilococos coagulasa negativa aislados de neonatos.
Bogado, I E; Marchiaro, P; Marzi, M; Putero, J; Ivancovich, J J; Sutich, E G.
Afiliação
  • Bogado IE; Departamento de Microbiología, Cátedra Microbiología Clínica I, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, República, Argentina. ibogado@arnet.com.ar
Enferm Infecc Microbiol Clin ; 19(4): 165-71, 2001 Apr.
Article em Es | MEDLINE | ID: mdl-11333603
OBJECTIVE: Neonates represent a high risk population for infections by coagulase-negative staphylococci (CNS). To have a better understanding of these process our purpose was to compare the expected result of the bacterium-host interaction given by the neonates' risks factors and the micro-organisms' virulence factors with the condition of infecting or colonising strain that emerge from the diagnosis on the basis of the clinical symptoms. METHODS: We studied 24 neonates who were submitted to an epidemiological control establishing as risk factors: catheters, vesicle sounds, previous surgery and immunodepressed conditions. In the CNS recovered from clinical samples we determined the following virulence factors: synergistic hemolysis, slime production, adherence to Teflon catheters and hydrophobicity. RESULTS: We found correlation between the clinical diagnosis and the expected result of the bacterium-host interaction in 21 patients (87.5%). Among them, in 8 patients infection didn't occurred in spite of having the micro-organisms 3 from 4 virulence factors since the patients didn't have risk factors. CONCLUSIONS: A microbiological study based entirely on identification and treatment can alter the biological context. It is necessary to understand the bacterium-host interaction for an appropriate comprehension of the bacterial diseases.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estafilocócicas / Staphylococcus Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans / Newborn Idioma: Es Revista: Enferm Infecc Microbiol Clin Assunto da revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Ano de publicação: 2001 Tipo de documento: Article País de afiliação: Argentina País de publicação: Espanha
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Estafilocócicas / Staphylococcus Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans / Newborn Idioma: Es Revista: Enferm Infecc Microbiol Clin Assunto da revista: DOENCAS TRANSMISSIVEIS / MICROBIOLOGIA Ano de publicação: 2001 Tipo de documento: Article País de afiliação: Argentina País de publicação: Espanha