[Hypercalcemia due to adult T-cell lymphoma in a man from Surinam]. / Hypercalciëmie door adult T-cellymfoom bij een Surinaamse man.
Ned Tijdschr Geneeskd
; 145(8): 370-4, 2001 Feb 24.
Article
em Nl
| MEDLINE
| ID: mdl-11257818
A 48-year-old male patient from Surinam presented with anorexia, nausea and weight loss. An extreme hypercalcaemia of 5.08 mmol/l was found. Further diagnostic investigations showed that this patient had a HTLV-1 positive adult T-cell leukaemia/lymphoma (ATL/L). This is often associated with multilobularly nucleated lymphocytes, bone destruction and hypercalcaemia. Skin localisations are frequently observed. The combination of cytomorphology, immunophenotyping, HTLV-1 seropositivity and clinical findings points to the diagnosis. The patient was treated with 6 courses of chemotherapy consisting of cyclophosphamide, doxorubicin, teniposide, prednisone, vincristine and bleomycin. Upon inquiry it appeared that he had died elsewhere. Chemotherapy induces a short-lived remission in a minority of ATL/L patients. Antiviral therapy (alpha interferon, zidovudine) might offer new possibilities.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anticorpos Anti-HTLV-I
/
Leucemia-Linfoma de Células T do Adulto
/
Hipercalcemia
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
/
Middle aged
País/Região como assunto:
America do sul
/
Caribe ingles
/
Suriname
Idioma:
Nl
Revista:
Ned Tijdschr Geneeskd
Ano de publicação:
2001
Tipo de documento:
Article
País de publicação:
Holanda