Differences between coding and non-coding regions in the Trichomonas vaginalis genome: an actin gene as a locus model(1).
Acta Trop
; 78(2): 147-54, 2001 Feb 23.
Article
em En
| MEDLINE
| ID: mdl-11230824
The sequence of a cloned genomic fragment of Trichomonas vaginalis containing a complete actin gene was determined. An uninterrupted open reading frame of 1128 nucleotides was found that codes for an actin gene. Two overlapped consensus promoter sequences for T. vaginalis were found 12 nucleotides upstream the actin initiation codon. In addition to actin, two incomplete open reading frames were found at the 5' and 3' ends of the clone. These two sequences are expressed and showed similarity to adenylate cyclase genes and a yeast hypothetical protein. The overall sequence showed a higher G+C content and a lower frequency of repeated sequences in the coding regions when compared with the non-coding regions. A similar unequal nucleotide distribution was found in various T. vaginalis genes retrieved from data bases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Trichomonas vaginalis
/
Actinas
Limite:
Animals
Idioma:
En
Revista:
Acta Trop
Ano de publicação:
2001
Tipo de documento:
Article
País de afiliação:
México
País de publicação:
Holanda