Human antibody response to a 56-kDa purified excretory/secretory product of Dirofilaria immitis.
Trop Med Int Health
; 5(12): 855-9, 2000 Dec.
Article
em En
| MEDLINE
| ID: mdl-11169274
Canine dirofilariasis is widespread in urban areas of central and northern Colombia. Previously we detected specific antibodies against complex antigens from Dirofilaria immitis adult worms in individuals from an isolated Tikuna Indian community in the Colombian Amazon. In this study a 56 kDa polypeptide from the adult D. immitis excretory/secretory (E/S) products is identified by Western blot, isolated by elution from polyacrilamide gels and applied in an ELISA-based test for the detection of specific IgG. Eleven of 74 serum samples analysed were positive by ELISADi56. Positive individuals came from five different areas of Colombia. The highest number of positives was found in the Amazon (4), followed by Bogotà (3). The physicians of the area must be alerted regarding the existence of human D. immitis infections and include dirofilariasis in the differential diagnosis of pulmonary nodules.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anticorpos Anti-Helmínticos
/
Dirofilaria immitis
/
Dirofilariose
Limite:
Animals
/
Humans
País/Região como assunto:
America do sul
/
Colombia
Idioma:
En
Revista:
Trop Med Int Health
Assunto da revista:
MEDICINA TROPICAL
/
SAUDE PUBLICA
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Espanha
País de publicação:
Reino Unido