The syndrome of multiple aucosal neuromas and medullary thyroid carcinoma in childhood. Importance of recognition of the phenotype for the early detection of malignancy.
J Pediatr
; 86(1): 77-83, 1975 Jan.
Article
em En
| MEDLINE
| ID: mdl-1110451
Recognition of the syndrome of OF MMN can identify individuals at risk for the early appearance of MTC. Three such patients are described. Each had the characteristic neuromas and facies, present since infancy. In each, MTC was found in childhood. In the last two patients, the diagnosis was made because of elevated serum CT concentrations. Venous drainage from the tumor, as well as tumor tissue itself, contained high levels of CT. Prompt recognition of persons with MMN is essential for proper investigation and treatment of the associated MTC.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Glândula Tireoide
/
Carcinoma
/
Mucosa
/
Neuroma
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Adolescent
/
Child
/
Female
/
Humans
Idioma:
En
Revista:
J Pediatr
Ano de publicação:
1975
Tipo de documento:
Article
País de publicação:
Estados Unidos