Comparison of five methods for the detection of measles specific immunoglobulin G antibody.

Vázquez-Rosales, J G; Solórzano-Santos, F; Bustamante-Calvillo, M E; Torres-López, J; Díaz-Ponce, H; Muñoz, O; Alvarez-Muñoz, M T

Vázquez-Rosales, J G; Solórzano-Santos, F; Bustamante-Calvillo, M E; Torres-López, J; Díaz-Ponce, H; Muñoz, O; Alvarez-Muñoz, M T.

Afiliação

Vázquez-Rosales JG; Unidad de Investigacion Médica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatria del Centro Médico Nacional Siglo XXI, del Instituto Mexicano del Seguro Social, México D. F.

Rev Latinoam Microbiol ; 38(3-4): 167-75, 1996.

Article em En | MEDLINE | ID: mdl-10932707

RESUMO

In this work we compare the sensitivity, specificity and predictive values of hemagglutination inhibition (HI), immunofluorescent assay (IFA), biotin-streptavidin immunofluorescent assay (B/SA-IFA), enzyme-linked immunosorbent assay (EIA) and plaque neutralization test (PN). This study includes serum samples from children taken before and after vaccination, children with clinically diagnosed measles and household contacts. EIA were the most specific and better serological diagnostic test. HI and IFA had high sensitivity but low specificity. An alternative to EIA is B/SAIFA, which is cheaper than EIA and can be used in the study of small outbreaks or in isolated cases.

Assuntos

Imunoglobulina G/sangue; Vírus do Sarampo/imunologia; Sarampo/sangue; Criança; Humanos; Valor Preditivo dos Testes; Sensibilidade e Especificidade; Testes Sorológicos/métodos

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Sarampo / Vírus do Sarampo Tipo de estudo: Diagnostic_studies Limite: Child / Humans Idioma: En Revista: Rev Latinoam Microbiol Ano de publicação: 1996 Tipo de documento: Article País de publicação: México

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