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[Diagnostic of congenital syphilis: a comparison between serological tests in mothers and their newborns]. / Diagnóstico de sífilis congênita: comparação entre testes sorológicos na mãe e no recém-nascido.
Barsanti, C; Valdetaro, F; de Albuquerque Diniz, E M; Succi, R C.
Afiliação
  • Barsanti C; Casa de Saúde Santa Marcelina, São Paulo, SP. barsanti@uol.com.br
Rev Soc Bras Med Trop ; 32(6): 605-11, 1999.
Article em Pt | MEDLINE | ID: mdl-10881096
For the purpose of establishing the incidence of maternal and congenital syphilis among pregnant women at delivery and their respective newborns, a study was carried out to determine treponemic and non-treponemic serology in one thousand (1,000) parturient women and their children at Santa Marcelina Hospital - São Paulo, between June 95 and July 96. All blood samples (maternal venous, umbilical cord and newborn venous) were VDRL-tested, treponemic tests (TPHA, ELISA IgG, ELISA IgM) being applied whenever one of the samples from mother or newborn proved positive. Further, an anti-HIV search was run through ELISA among VDRL-positive mothers. Among the 1,000 parturients, 24 (2.4%) were found to be VDRL-reactive; 18 (1.8%) newborn children of these 24 mothers presented positive serology in their umbilical cord blood and 19 (1.9%) in venous blood. No positive newborns were found for negative mothers. From the high occurrence of maternal and congenital syphilis in this group of patients, we propose a VDRL maternal test as a way of selecting gestational and congenital syphilis cases, since this test appeared to be sufficiently capable of such diagnoses. Of the treponemic tests, the ELISA test did not enhance diagnostic sensitivity.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sífilis Congênita / Sorodiagnóstico da Sífilis Tipo de estudo: Diagnostic_studies Limite: Adult / Female / Humans / Newborn / Pregnancy Idioma: Pt Revista: Rev Soc Bras Med Trop Ano de publicação: 1999 Tipo de documento: Article País de publicação: Brasil
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sífilis Congênita / Sorodiagnóstico da Sífilis Tipo de estudo: Diagnostic_studies Limite: Adult / Female / Humans / Newborn / Pregnancy Idioma: Pt Revista: Rev Soc Bras Med Trop Ano de publicação: 1999 Tipo de documento: Article País de publicação: Brasil