Biotransformation of methyl ent-17-hydroxy-16beta-kauran-19-oate by Rhizopus stolonifer.

Vieira, H S; Takahashi, J A; Boaventura, M A

Vieira, H S; Takahashi, J A; Boaventura, M A.

Afiliação

Vieira HS; Departamento de Química, ICEx, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Appl Microbiol Biotechnol ; 53(5): 601-4, 2000 May.

Article em En | MEDLINE | ID: mdl-10855722

RESUMO

Methyl ent-17-hydroxy-16beta-kauran-19-oate was fed to a 2-day-old culture of the fungus Rhizopus stolonifer, fermenting at room temperature (25 degrees C) in an orbital shaker (21). After 11 days, both broth and mycelia were extracted with ethyl acetate. Two novel compounds were isolated from this experiment: methyl ent-9alpha,17-dihydroxy-16beta-kauran-19-oate and methyl ent-7alpha,17-dihydroxy-16beta-kauran-19-oate. Their structures were fully confirmed by spectroscopic methods.

Assuntos

Diterpenos/metabolismo; Rhizopus/crescimento & desenvolvimento; Rhizopus/metabolismo; Biotransformação; Meios de Cultura; Espectroscopia de Ressonância Magnética

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rhizopus / Diterpenos Idioma: En Revista: Appl Microbiol Biotechnol Ano de publicação: 2000 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha

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