[Thrombotic thrombocytopenic purpura and systemic lupus erythematous. Three cases presenting simultaneously]. / Púrpura trombocitopenica trombótica y lupus eritematoso sistémico. Tres casos con presentación simultánea.
Medicina (B Aires)
; 59(6): 739-42, 1999.
Article
em Es
| MEDLINE
| ID: mdl-10752218
Thrombotic thrombocytopenic purpura (TTP) is a clinical syndrome characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever, neurological symptoms, and renal involvement. The relationship of TTP to systemic lupus erythematosus (SLE) has been recognized in the medical literature since 1939. The differential diagnosis is difficult because both diseases have similar clinical features. The mainstay for recognizing TTP in the context of active SLE is the presence of helmet red cells, marked reticulocytosis, and negative direct Coomb's test. We report three female patients with simultaneous presentation of TTP and SLE. We suggest combined treatment with immunosuppressive therapy and plasma exchange using fresh frozen plasma.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Púrpura Trombocitopênica Trombótica
/
Lúpus Eritematoso Sistêmico
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
Es
Revista:
Medicina (B Aires)
Ano de publicação:
1999
Tipo de documento:
Article
País de publicação:
Argentina