How Echinococcus granulosus deals with complement.
Parasitol Today
; 16(4): 168-72, 2000 Apr.
Article
em En
| MEDLINE
| ID: mdl-10725905
Here, Ana Mar a Ferreira and colleagues discuss the interplay between the larval stages of Echinococcus granulosus and an important effector arm of immunity: the host complement system. During early infection, the parasite activates complement, and hence complement-dependent inflammatory responses. However, on differentiation into the hydatid cyst, the parasite exposes to the host a structure - the cyst wall - that does not activate complement strongly. Mechanisms inhibiting complement activation on the cyst wall have been elucidated, contributing to the understanding of how this large, persistent, tissue-dwelling pathogen controls the inflammatory response.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ativação do Complemento
/
Equinococose
/
Echinococcus
Limite:
Animals
Idioma:
En
Revista:
Parasitol Today
Assunto da revista:
PARASITOLOGIA
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Uruguai
País de publicação:
Reino Unido