Measles epidemiology and outbreak response immunization in a rural community in Peru.
Bull World Health Organ
; 77(7): 545-52, 1999.
Article
em En
| MEDLINE
| ID: mdl-10444877
ABSTRACT
PIP: A community survey of the epidemiology and impact of measles outbreak response immunization (ORI) in Espindola, Peru. Blood specimens from 29 clinical cases having the onset of symptoms within 5 weeks to collection were tested for the anti-measles virus nucleoprotein antibody. Questionnaires were given to the head of the household and the 29 clinical cases to identify clinical symptoms an disease outcomes and to determine vaccination coverage. Attack rates, vaccine effectiveness, and predictive value positive was also calculated. Findings showed that primary cases were frequent among adults, who accounted for 44% of cases. The attack rate among all susceptible people was 45.5% and was highest among adults aged 16-20 (61.2%). For the serologically confirmed cases, 60.7% developed diarrhea and 32.1% pneumonia. Case fatality rate was 19.1% for children aged 0-23 months and 1.5% for adults aged 16-40 years. The lack of national campaigns or access to routine immunization caused the severe impact of measles virus outbreak. The ORI campaign targeted nonmeasles case children aged 6 months to 15 years regardless of immunization status, which was effective in terminating measles outbreak, morbidity, and mortality. This campaign cost approximately US$3000 and in 1998 saved 1155 person-days of work among 77 adults. It also prevented 87 diarrhea and 46 pneumonia cases and averted 5 deaths.
Palavras-chave
Americas; Case Fatality Rate; Community Surveys; Death Rate; Delivery Of Health Care; Demographic Factors; Developing Countries; Diseases; Epidemiologic Methods; Health; Health Services; Immunization; Latin America; Measles; Measurement; Mortality; Peru; Population; Population Characteristics; Population Dynamics; Prevalence; Primary Health Care; Research Methodology; Research Report; Rural Population; Sampling Studies; South America; Studies; Surveys; Vaccines--administraction and dosage; Viral Diseases
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vacina contra Sarampo
/
Surtos de Doenças
/
Sarampo
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Limite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
America do sul
/
Peru
Idioma:
En
Revista:
Bull World Health Organ
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Estados Unidos
País de publicação:
Suíça