alpha-Interferon therapy for HBV-related glomerulonephritis.
Sao Paulo Med J
; 116(5): 1823-5, 1998.
Article
em En
| MEDLINE
| ID: mdl-10030109
We report a case of a patient with hepatitis B virus (HBV)-related membranous glomerulonephritis (MGN) who showed improvement after interferon-alpha (IFN-alpha) therapy. A 35-year-old man with nephrotic syndrome and HBV antigens received a 24-week course of IFN-alpha. At the end of therapy there was an elevation in the level of plasma aminotransferase and an increase in proteinuria, which were followed by antigen/antibody seroconversion. This "flare-up" before seroconversion suggests an increase in disease activity in the liver and kidney, demonstrating in vivo HBV involvement in MGN.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antivirais
/
Glomerulonefrite Membranosa
/
Interferon-alfa
/
Hepatite B
Limite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Sao Paulo Med J
Assunto da revista:
MEDICINA
Ano de publicação:
1998
Tipo de documento:
Article
País de publicação:
Brasil