Effect of fencamfamine on avoidance performances of rats
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;24(3): 307-9, mar. 1991. tab
Article
em En
| LILACS
| ID: lil-99569
Biblioteca responsável:
BR26.1
ABSTRACT
The effects of fencamfamine (1.0 and 5.0 mg/kg, ip single dose) on an inhibitory task were studied in rats (N=15 per group).Post-training treatment with fencamfamine (1.0 mg/kg) significantly increased avoidance latency from 23 ñ 3 to 146 ñ 28 and 170 ñ 33 s for training day 1 and day 7, respectively, indicating an enhacement of retention.However, retention was significantly reduced with a high dose of fencamfamine (5.0 mg/kg). These results demonstrate that fencamfamine caused a reproducible dose-related increase and reduction in avoidance latency
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Retenção Psicológica
/
Aprendizagem da Esquiva
/
Reação de Fuga
/
Norbornanos
Limite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
/
Rev. bras. pesqui. méd. biol
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
1991
Tipo de documento:
Article
País de publicação:
Brasil