Neuropsychiatric manifestations of systemic lupus erythematosus: the value of anticardiolipin, antigangliosides and antigalactocerebrosides antibodies
Rev. bras. reumatol
; Rev. bras. reumatol;29(4): 151-7, jul.-ago. 1989. tab
Article
em En
| LILACS
| ID: lil-80469
Biblioteca responsável:
BR1.1
ABSTRACT
In an attempt to find a serological marker for neuropsychiatric manifestations (NPM) of SLE sera from 66 patients (classified in three groups, according to their NPM - defined, probable and without NPM) were analysed by ELISA for IgG and antigalactocerebrosides antibodies. A strong correlation was found between IgM antigangliosides and antigalactocerebrosides antibodies and NPM, but not with IgG class. IgM and IgG antibodies anticardiolipin were not correlated with BPM in this study. Both IgM antigangliosides and seven patients with definid NPM but clinically inactive. The analysis of these autoantibodies showed an important role predictive for NPM in SLE; the negative test decreases the chance of the NPM
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Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Cardiolipinas
/
Anticorpos Anti-Idiotípicos
/
Galactosilceramidas
/
Gangliosídeos
/
Lúpus Eritematoso Sistêmico
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Rev. bras. reumatol
Assunto da revista:
REUMATOLOGIA
Ano de publicação:
1989
Tipo de documento:
Article
País de publicação:
Brasil