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Neuropsychiatric manifestations of systemic lupus erythematosus: the value of anticardiolipin, antigangliosides and antigalactocerebrosides antibodies
Rev. bras. reumatol ; Rev. bras. reumatol;29(4): 151-7, jul.-ago. 1989. tab
Article em En | LILACS | ID: lil-80469
Biblioteca responsável: BR1.1
ABSTRACT
In an attempt to find a serological marker for neuropsychiatric manifestations (NPM) of SLE sera from 66 patients (classified in three groups, according to their NPM - defined, probable and without NPM) were analysed by ELISA for IgG and antigalactocerebrosides antibodies. A strong correlation was found between IgM antigangliosides and antigalactocerebrosides antibodies and NPM, but not with IgG class. IgM and IgG antibodies anticardiolipin were not correlated with BPM in this study. Both IgM antigangliosides and seven patients with definid NPM but clinically inactive. The analysis of these autoantibodies showed an important role predictive for NPM in SLE; the negative test decreases the chance of the NPM
Assuntos
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Coleções: 01-internacional Base de dados: LILACS Assunto principal: Cardiolipinas / Anticorpos Anti-Idiotípicos / Galactosilceramidas / Gangliosídeos / Lúpus Eritematoso Sistêmico Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Male Idioma: En Revista: Rev. bras. reumatol Assunto da revista: REUMATOLOGIA Ano de publicação: 1989 Tipo de documento: Article País de publicação: Brasil
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Coleções: 01-internacional Base de dados: LILACS Assunto principal: Cardiolipinas / Anticorpos Anti-Idiotípicos / Galactosilceramidas / Gangliosídeos / Lúpus Eritematoso Sistêmico Tipo de estudo: Diagnostic_studies Limite: Female / Humans / Male Idioma: En Revista: Rev. bras. reumatol Assunto da revista: REUMATOLOGIA Ano de publicação: 1989 Tipo de documento: Article País de publicação: Brasil