Your browser doesn't support javascript.
loading
Major bleeding risk assessment in atrial fibrillation patients taking vitamin K antagonists
Pivatto Júnior, Fernando; Silva, André Luís Ferreira da; Bezerra, Indira Valente; Pires, Leonardo Martins; Amon, Luís Carlos; Blaya, Marina Bergamini; Scheffel, Rafael Selbach.
Afiliação
  • Pivatto Júnior, Fernando; Hospital de Clínicas de Porto Alegre. Department of Internal Medicine. Porto Alegre. BR
  • Silva, André Luís Ferreira da; Hospital de Clínicas de Porto Alegre. Department of Internal Medicine. Porto Alegre. BR
  • Bezerra, Indira Valente; Hospital de Clínicas de Porto Alegre. Department of Internal Medicine. Porto Alegre. BR
  • Pires, Leonardo Martins; Hospital de Clínicas de Porto Alegre. Department of Internal Medicine. Porto Alegre. BR
  • Amon, Luís Carlos; Hospital de Clínicas de Porto Alegre. Department of Internal Medicine. Porto Alegre. BR
  • Blaya, Marina Bergamini; Hospital de Clínicas de Porto Alegre. Department of Internal Medicine. Porto Alegre. BR
  • Scheffel, Rafael Selbach; Hospital de Clínicas de Porto Alegre. Department of Internal Medicine. Porto Alegre. BR
Clin. biomed. res ; 35(2): 99-103, 2015. ilus, tab
Article em En | LILACS | ID: lil-780249
Biblioteca responsável: BR18.1
ABSTRACT
The use of risk scores for the assessment of major bleeding and stroke in patients with atrial fibrillation (AF) helps evaluate the risks and benefits of oral anticoagulation therapy. The aim of this study was to describe the percentage of patients receiving anticoagulants for non-valvular AF with a high risk of major bleeding based on the HAS-BLED score, as well as identify potential modifiable risk factors of bleeding and compare the risk of major bleeding with the risk of stroke.

Methods:

Retrospective cohort study involving patients of the anticoagulation outpatient clinic of the Division of Internal Medicine at Hospital de Clínicas de Porto Alegre. Major bleeding risk was estimated based on the HAS-BLED score and stroke risk was determined using the CHADS2 and CHA2 DS2 -VASc scores.

Results:

Sixty-three patients were investigated (mean age 74.3±10.9 years). The median HAS-BLED score was 2 points, 19 (30.2%) patients had a score ≥ 3 (high risk). The most prevalent modifiable risk factors were labile TP/INR (36.5%) and concomitant use of drugs (30.2%). The absolute risk of major bleeding based on the HAS-BLED score was higher than the risk of stroke in three (4.8%) and four (6.3%) patients in comparison with the CHADS2 and CHA2 DS2 -VASc score, respectively.

Conclusions:

We concluded that the percentage of patients with high risk of major bleeding is similar to the rate found in the national literature (30.2%). In addition, the most prevalent modifiable risk factors in our cohort were labile TP/INR and concomitant drug use...
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Fibrilação Atrial / Acidente Vascular Cerebral / Anticoagulantes Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Clin. biomed. res Assunto da revista: MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Fibrilação Atrial / Acidente Vascular Cerebral / Anticoagulantes Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Clin. biomed. res Assunto da revista: MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil