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Association of human papillomavirus and Chlamydia trachomatis with intraepithelial alterations in cervix samples
Wohlmeister, Denise; Vianna, Débora Renz Barreto; Helfer, Virgínia Etges; Gimenes, Fabrícia; Consolaro, Marcia Edilaine Lopes; Barcellos, Regina Bones; Rossetti, Maria Lucia; Calil, Luciane Noal; Buffon, Andréia; Pilger, Diogo André.
Afiliação
  • Wohlmeister, Denise; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Vianna, Débora Renz Barreto; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Helfer, Virgínia Etges; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Gimenes, Fabrícia; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Consolaro, Marcia Edilaine Lopes; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Barcellos, Regina Bones; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Rossetti, Maria Lucia; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Calil, Luciane Noal; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Buffon, Andréia; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
  • Pilger, Diogo André; Universidade Federal do Rio Grande do Sul. Porto Alegre. BR
Mem. Inst. Oswaldo Cruz ; 111(2): 106-113, Feb. 2016. tab, graf
Article em En | LILACS | ID: lil-772612
Biblioteca responsável: BR1.1
ABSTRACT
The influence of different infectious agents and their association with human papillomavirus (HPV) in cervical carcinogenesis have not been completely elucidated. This study describes the association between cytological changes in cervical epithelium and the detection of the most relevant aetiological agents of sexually transmitted diseases. Samples collected from 169 patients were evaluated by conventional cytology followed by molecular analysis to detect HPV DNA, Chlamydia trachomatis, herpes simplex virus 1 and 2,Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis, andTreponema pallidum, besides genotyping for most common high-risk HPV. An association between cytological lesions and different behavioural habits such as smoking and sedentariness was observed. Intraepithelial lesions were also associated with HPV and C. trachomatis detection. An association was also found between both simple and multiple genotype infection and cytological changes. The investigation of HPV and C. trachomatisproved its importance and may be considered in the future for including in screening programs, since these factors are linked to the early diagnosis of patients with precursor lesions of cervical cancer.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Papillomaviridae / DNA Viral / Neoplasias do Colo do Útero / Colo do Útero / Chlamydia trachomatis / Lesões Intraepiteliais Escamosas Cervicais Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Adult / Female / Humans Idioma: En Revista: Mem. Inst. Oswaldo Cruz Assunto da revista: MEDICINA TROPICAL / PARASITOLOGIA Ano de publicação: 2016 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Papillomaviridae / DNA Viral / Neoplasias do Colo do Útero / Colo do Útero / Chlamydia trachomatis / Lesões Intraepiteliais Escamosas Cervicais Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Adolescent / Adult / Female / Humans Idioma: En Revista: Mem. Inst. Oswaldo Cruz Assunto da revista: MEDICINA TROPICAL / PARASITOLOGIA Ano de publicação: 2016 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil