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Tuberculosis contact tracing among children and adolescent referred to children's hospital in Rio de Janeiro, Brazil
Mendonça, Angela Marcia Cabral; Kritski, Afrânio Lineu; Sant'Anna, Clemax Couto.
Afiliação
  • Mendonça, Angela Marcia Cabral; Universidade Federal do Rio de Janeiro. School of Medicine. Rio de Janeiro. BR
  • Kritski, Afrânio Lineu; Universidade Federal do Rio de Janeiro. School of Medicine. Rio de Janeiro. BR
  • Sant'Anna, Clemax Couto; Universidade Federal do Rio de Janeiro. School of Medicine. Rio de Janeiro. BR
Braz. j. infect. dis ; Braz. j. infect. dis;19(3): 296-301, May-Jun/2015. tab
Article em En | LILACS | ID: lil-751880
Biblioteca responsável: BR1.1
ABSTRACT

Objective:

To describe the investigation of latent tuberculosis infection and indication for isoniazid preventive therapy in children and adolescents evaluated at the children's hospital.

Methods:

This retrospective study examines all latent tuberculosis infection subjects with indication for isoniazid preventive therapy attended during 2002-2009 at the pulmonology outpatient clinic from children's hospital in Rio de Janeiro, Brazil. The subjects were classified into three groups by origin (G1) primary and secondary health units; (G2) children's hospital-pulmonology outpatient clinic; and (G3) children's hospital-specialty outpatient clinics. The association between the variables examined and G1 was analyzed using uni- variate analysis.

Results:

Of the 286 latent tuberculosis infection cases included 169 (59.1%) were from G1, 56 (19.6%) from G2, and 61 (21.3%) from G3. Latent tuberculosis infection diagnosis without isoniazid preventive therapy prescription was present in 142 (49.6%) cases before arrival at the pulmonology outpatient clinic 135 (95.1%) from G1, three (2.1%) from G2, and four (2.8%) from G3. Variables associated with G1 were presence of isoniazid preventive therapy criteria before attending the pulmonology outpatient clinic (OR 62.3; 26.6-146.2), negative HIV infection status (OR 9.44; 1.16-76.3); contact with pulmonary tuberculosis (OR 5.57; 1.99-15.5), and residing in Rio de Janeiro city (OR 1.89; 1.04-3.44).

Conclusion:

Strategies that increase latent tuberculosis infection identification and isoniazid preventive therapy prescription in primary and secondary health units are urgently needed. .
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Tuberculose Pulmonar / Busca de Comunicante / Tuberculose Latente / Isoniazida / Antituberculosos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Braz. j. infect. dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Tuberculose Pulmonar / Busca de Comunicante / Tuberculose Latente / Isoniazida / Antituberculosos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Braz. j. infect. dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil