Effect of salt intake and potassium supplementation on brachial-ankle pulse wave velocity in Chinese subjects: an interventional study

Wang, Y.; Mu, J.J.; Geng, L.K.; Wang, D.; Ren, K.Y.; Guo, T.S.; Chu, C.; Xie, B.Q.; Liu, F.Q.; Yuan, Z.Y.

Wang, Y.; Mu, J.J.; Geng, L.K.; Wang, D.; Ren, K.Y.; Guo, T.S.; Chu, C.; Xie, B.Q.; Liu, F.Q.; Yuan, Z.Y..

Afiliação

Wang, Y.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Mu, J.J.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Geng, L.K.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Wang, D.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Ren, K.Y.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Guo, T.S.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Chu, C.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Xie, B.Q.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Liu, F.Q.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN
Yuan, Z.Y.; First Affiliated Hospital of Medical College, Xi'an Jiaotong University. Cardiovascular Department. Xi'an. CN

Rev. bras. pesqui. méd. biol ; Braz. j. med. biol. res;48(1): 83-90, 01/2015. tab, graf

Article em En | LILACS | ID: lil-730437

Biblioteca responsável: BR1.1

ABSTRACT

ABSTRACT

Accumulating evidence has suggested that high salt and potassium might be associated with vascular function. The aim of this study was to investigate the effect of salt intake and potassium supplementation on brachial-ankle pulse wave velocity (PWV) in Chinese subjects. Forty-nine subjects (28-65 years of age) were selected from a rural community of northern China. All subjects were sequentially maintained on a low-salt diet for 7 days (3.0 g/day NaCl), a high-salt diet for an additional 7 days (18.0 g/day NaCl), and a high-salt diet with potassium supplementation for a final 7 days (18.0 g/day NaCl+4.5 g/day KCl). Brachial-ankle PWV was measured at baseline and on the last day of each intervention. Blood pressure levels were significantly increased from the low-salt to high-salt diet, and decreased from the high-salt diet to high-salt plus potassium supplementation. Baseline brachial-ankle PWV in salt-sensitive subjects was significantly higher than in salt-resistant subjects. There was no significant change in brachial-ankle PWV among the 3 intervention periods in salt-sensitive, salt-resistant, or total subjects. No significant correlations were found between brachial-ankle PWV and 24-h sodium and potassium excretions. Our study indicates that dietary salt intake and potassium supplementation, at least in the short term, had no significant effect on brachial-ankle PWV in Chinese subjects.

Palavras-chave

Interventional study; Potassium; Pulse wave velocity; Salt

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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Idioma: En Revista: Braz. j. med. biol. res / Rev. bras. pesqui. méd. biol Assunto da revista: BIOLOGIA / MEDICINA Ano de publicação: 2015 Tipo de documento: Article / Project document País de afiliação: China País de publicação: Brasil

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