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Urinary Symptoms and Urodynamics Findings in Patients with Friedreich's Ataxia
Musegante, Andre F. A.; Almeida, Priscila Natasja S.; Monteiro, Raphael Temporao M.; Barroso Jr, Ubirajara.
Afiliação
  • Musegante, Andre F. A.; Brasilia and Bahiana University of Bahia (UBjr). Salvador; SARAH Network of Rehabilitation Hospitals (RTMM). SARAH Network of Rehabilitation Hospitals (AFAM, PNSA). Salvador. BR
  • Almeida, Priscila Natasja S.; Brasilia and Bahiana University of Bahia (UBjr). Salvador; SARAH Network of Rehabilitation Hospitals (RTMM). SARAH Network of Rehabilitation Hospitals (AFAM, PNSA). Salvador. BR
  • Monteiro, Raphael Temporao M.; Brasilia and Bahiana University of Bahia (UBjr). Salvador; SARAH Network of Rehabilitation Hospitals (RTMM). SARAH Network of Rehabilitation Hospitals (AFAM, PNSA). Salvador. BR
  • Barroso Jr, Ubirajara; Brasilia and Bahiana University of Bahia (UBjr). Salvador; SARAH Network of Rehabilitation Hospitals (RTMM). SARAH Network of Rehabilitation Hospitals (AFAM, PNSA). Salvador. BR
Int. braz. j. urol ; 39(6): 867-874, Nov-Dec/2013. tab, graf
Article em En | LILACS | ID: lil-699120
Biblioteca responsável: BR1.1
ABSTRACT
Purpose To assess the prevalence of LUTS, urinary tract and urodynamics changes in patients with Friedreich's Ataxia (FA), the most common form of hereditary ataxia. Materials and Methods This study evaluated 258 patients with genetically confirmed diagnoses of FA. Of the patients, 158 responded to a questionnaire which assessed their urinary symptoms. Patients with clinical changes underwent renal function examinations, ultrasound, and urodynamic studies (UDS). Results The sample analyzed showed that 82% of the patients complained of LUTS, although only 22% related the symptoms with quality of life impairment. Twenty eight (18%) of them agreed to undergo urodynamic evaluation. Urgency was the most common symptom. The exam was normal in 4 (14%) and detrusor underactivity was the most common finding. 14% (4 patients) presented with dilatation of the upper urinary tract at ultrasound scans. None of them had creatinine alterations. Conclusions LUTS was found in a large percentage of patients with FA, but only a few related it to their quality of life impairment. Although creatinine levels was normal in this sample, some patients may show upper urinary tract abnormalities, with deserves close observation and proper care. .
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Urodinâmica / Bexiga Urinária / Ataxia de Friedreich / Sintomas do Trato Urinário Inferior Tipo de estudo: Diagnostic_studies / Prevalence_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adult / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Int. braz. j. urol Assunto da revista: UROLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Urodinâmica / Bexiga Urinária / Ataxia de Friedreich / Sintomas do Trato Urinário Inferior Tipo de estudo: Diagnostic_studies / Prevalence_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adult / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Int. braz. j. urol Assunto da revista: UROLOGIA Ano de publicação: 2013 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil