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Polycystic echinococcosis in the state of Acre, Brazil: contribution to patient diagnosis, treatment and prognosis
Memorias do Instituto Oswaldo Cruz; Siqueira, Nilton Ghiotti de; Siqueira, Claudia Maria Villar Maziero de; Rodrigues-Silva, Rosangela; Soares, Manoel do Carmo P; Povoa, Marinete Marins.
Afiliação
  • Siqueira, Nilton Ghiotti de; Universidade Federal do Acre. Rio Branco. BR
  • Siqueira, Claudia Maria Villar Maziero de; Universidade Federal do Acre. Rio Branco. BR
  • Rodrigues-Silva, Rosangela; Universidade Federal do Acre. Rio Branco. BR
  • Soares, Manoel do Carmo P; Universidade Federal do Acre. Rio Branco. BR
  • Povoa, Marinete Marins; Universidade Federal do Acre. Rio Branco. BR
Mem. Inst. Oswaldo Cruz ; 108(5): 533-540, ago. 2013. tab, graf
Article em En | LILACS | ID: lil-680778
Biblioteca responsável: BR1.1
ABSTRACT
The lack of knowledge regarding polycystic hydatid disease results in delayed or even incorrect diagnosis. The lack of systematic information regarding treatment also makes it difficult to assess the results and prognosis in patients with peritoneal and hepatic lesions caused by Echinococcus vogeli. Here we describe the clinical features of patients, propose a radiological classification protocol and describe a therapeutic option for the treatment of hydatid disease that previously had only been used for cases of cystic echinococcosis (Echinococcus granulosus). A prospective cohort study was initiated in 1999 and by 2009 the study included 60 patients. These patients were classified according to the PNM classification (parasite lesion, neighbouring organ invasion and metastases) and placed in one of three therapeutic modalities (i) chemotherapy with albendazole at a dose of 10 mg/kg/day, (ii) surgical removal of cysts or (iii) percutaneous puncture of the cysts via puncture, aspiration, injection and re-aspiration (PAIR). The results were stratified according to therapeutic

outcome:

"cure", "clinical improvement", "no improvement", "death" or "no information". The PNM classification was useful in indicating the appropriate therapy in cases of polycystic hydatid disease. In conclusion, surgical therapy produced the best clinical results of all the therapies studied based on "cure" and "clinical improvement" outcomes. The use of PAIR for treatment requires additional study.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Albendazol / Equinococose Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 / Animals / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Mem. Inst. Oswaldo Cruz Assunto da revista: MEDICINA TROPICAL / PARASITOLOGIA Ano de publicação: 2013 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Albendazol / Equinococose Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 / Animals / Female / Humans / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Mem. Inst. Oswaldo Cruz Assunto da revista: MEDICINA TROPICAL / PARASITOLOGIA Ano de publicação: 2013 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil