Peroneal nerve reconstruction by using glycerol-preserved veins: histological and functional assessment in rats
Acta cir. bras
; Acta cir. bras;28(2): 94-101, Feb. 2013. ilus, graf, tab
Article
em En
| LILACS
| ID: lil-662355
Biblioteca responsável:
BR1.1
ABSTRACT
PURPOSE:
To compare the degree of neural regeneration in rats upon interposition of autologous nerve graft, autogenous vein, glycerol-preserved autogenous vein, and glycerol-preserved allogeneic vein using qualitative and quantitative histological analyses as well as functional assessments.METHODS:
Peroneal nerves were reconstructed differently in four groups of animals. Functional assessments were performed pre- and postoperatively for a period of six weeks. After six weeks, the animals were sacrificed and histological evaluations were performed.RESULTS:
Histological patterns of autogenous veins without preservation showed pronounced neoangiogenesis and extensive axonal rarefaction, as confirmed by axonal counting and functional assessments. Glycerol-preserved veins had results similar to the control.CONCLUSIONS:
Glycerol-preserved autogenous or allogeneic veins showed similar results to autograft results. The autogenous vein (without preservation in glycerol) presented histological and functional outcomes statistically lower than other groups.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Nervo Fibular
/
Preservação de Tecido
/
Glicerol
/
Veias Jugulares
/
Regeneração Nervosa
Tipo de estudo:
Qualitative_research
Limite:
Animals
Idioma:
En
Revista:
Acta cir. bras
Assunto da revista:
Cirurgia Geral
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil