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Investigation of antioxidant and anti-glycation properties of essential oils from fruits and branchlets of Juniperus oblonga
Emami, Seyed A.; Asgary, Sedigheh; Naderi, Gholam A.; Ardekani, Mohammad R. S.; Aslani, Sanaz; Airin, Atousa; Kasher, Taghi; Sahebkar, Amirhossein.
Afiliação
  • Emami, Seyed A.; Mashhad University of Medical Sciences. School of Pharmacy. Department of Pharmacognosy. IR
  • Asgary, Sedigheh; Isfahan University of Medical Sciences. Isfahan Cardiovascular Research Center. IR
  • Naderi, Gholam A.; Isfahan University of Medical Sciences. Isfahan Cardiovascular Research Center. IR
  • Ardekani, Mohammad R. S.; Tehran University of Medical Sciences. School of Pharmacy. Department of Pharmacognosy. IR
  • Aslani, Sanaz; Isfahan University of Medical Sciences. School of Pharmacy.
  • Airin, Atousa; Isfahan University of Medical Sciences. School of Pharmacy.
  • Kasher, Taghi; Isfahan University of Medical Sciences. School of Pharmacy.
  • Sahebkar, Amirhossein; Mashhad University of Medical Sciences. Biotechnology Research Center and School of Pharmacy. IR
Rev. bras. farmacogn ; 22(5): 985-993, Sept.-Oct. 2012. graf, tab
Article em En | LILACS | ID: lil-649642
Biblioteca responsável: BR1.1
ABSTRACT
Plants represent the best and most extensively studied source of natural antioxidants. The present study investigated the antioxidant and anti-glycation properties of different concentrations of essential oils obtained from fruits and branchlets of Juniperus oblonga M. Bieb., Cupressaceae, using different assays. The essential oils were obtained by steam distillation of the branchlets of male tree (BMT), branchlets of female tree (BFT) and fruits of J. oblonga. Compositional analysis of oils was performed using a gas chromatography-mass method. Antioxidant activity was assessed using linoleic acid peroxidation, peroxyl radical mediated hemolysis of red blood cells (RBC) and low-density lipoprotein (LDL) oxidation assays. Anti-glycation properties of oils were evaluated using hemoglobin and insulin glycation assays. Seventeen, eighteen and fifteen compounds were identified in the BMT, BFT and fruit oil, which represented 82.51, 55.69 and 96.89% of the total oils, respectively. α-Pinene was the major component of all three oils. All three oils possessed antioxidant effects against LDL oxidation, linoleic acid peroxidation and peroxyl radical mediated RBC hemolysis. Anti-glycation activities against hemoglobin and insulin glycation were also observed from all tested oils. Overall, there was no unique pattern of dose-dependence for the antioxidant properties of oils in different employed systems. The findings of this study suggest that essential oils from fruits and branchlets of J. oblonga possess antioxidant and anti-glycation properties. Therefore, these oils might be of therapeutic efficacy against diabetes and cardiovascular disease.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Tipo de estudo: Prognostic_studies Idioma: En Revista: Rev. bras. farmacogn Assunto da revista: FARMACIA Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Irã País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Tipo de estudo: Prognostic_studies Idioma: En Revista: Rev. bras. farmacogn Assunto da revista: FARMACIA Ano de publicação: 2012 Tipo de documento: Article País de afiliação: Irã País de publicação: Brasil