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Antitumor properties of ganoderma lucidum polysaccharidesand terpenoids: [review]
Camargo, Marcela R; Kaneno, Ramon.
Afiliação
  • Camargo, Marcela R; Universidade Estadual Paulista. Institute of Biosciences,. Department of Microbiology and Immunology. Botucatu. BR
  • Kaneno, Ramon; Universidade Estadual Paulista. School of Medicine. Department of Pathology. Botucatu. BR
ARBS annu. rev. biomed. sci ; ARBS annu. rev. biomed. sci;13(n.esp): 1-8, 2011. tab
Article em En | LILACS | ID: lil-619902
Biblioteca responsável: BR33.1
ABSTRACT
Ganoderma lucidum is an edible medicinal mushroom withimmunomodulatory and antitumor properties, which are mainly attributed to polysaccharides and triterpenesthat can be isolated from mycelia, fruiting bodies and spores. G. lucidum has been used in a powdered form, asa medicinal beverage and a nutraceutical food (usually dried). In the present review we report some historicalfacts and the experimental evidence that polysaccharides and triterpenes obtained from this mushroom presentpotential antitumor activity. Direct effects on tumor cells include induction of apoptosis and interference in thecell cycle, whereas indirect effects are based on the modulation of immune response, usually impaired bycancer cells. Data indicate that G. lucidum can be used as a complementary tool for treatment of cancerpatients.
Assuntos
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Polissacarídeos / Triterpenos / Reishi / Agaricales / Fatores Imunológicos / Neoplasias Idioma: En Revista: ARBS annu. rev. biomed. sci Assunto da revista: BIOLOGIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Polissacarídeos / Triterpenos / Reishi / Agaricales / Fatores Imunológicos / Neoplasias Idioma: En Revista: ARBS annu. rev. biomed. sci Assunto da revista: BIOLOGIA Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil