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Perinatal morbidity and mortality associated with chlamydial infection: a meta-analysis study
Silva, Maria José Penna Maisonnette de Attayde; Florêncio, Gilzandra Lira Dantas; Gabiatti, José Roberto Erbolato; Amaral, Rose Luce do; Eleutério Júnior, José; Gonçalves, Ana Katherine da Silveira.
Afiliação
  • Silva, Maria José Penna Maisonnette de Attayde; Universidade Federal do Rio Grande do Norte. Postgraduate Program in Health Sciences.
  • Florêncio, Gilzandra Lira Dantas; Universidade Federal do Rio Grande do Norte. Postgraduate Program in Health Sciences.
  • Gabiatti, José Roberto Erbolato; Universidade Estadual de Campinas. Faculdade de Ciências Médicas. Tocoginecology Department. BR
  • Amaral, Rose Luce do; UNICAMP.
  • Eleutério Júnior, José; Universidade Federal do Ceará. BR
  • Gonçalves, Ana Katherine da Silveira; UFRN. BR
Braz. j. infect. dis ; Braz. j. infect. dis;15(6): 533-539, Nov.-Dec. 2011. tab
Article em En | LILACS | ID: lil-610523
Biblioteca responsável: BR1.1
ABSTRACT

OBJECTIVE:

To evaluate the effect of Chlamydia trachomatis infection during pregnancy on perinatal morbidity and mortality.

METHODS:

Systematic review and meta-analysis in an electronic database and manual, combining high sensitivity specific descriptors seeking to answer the research objective. The articles considered to be of high methodological quality (score above 6 on the Newcastle-Ottawa Scale) were assessed by meta-analysis.

RESULTS:

Summary estimates of 12 studies were calculated by means of Mantel-Haenszel test with 95 percent confidence interval. It was observed that Chlamydia infection during pregnancy increased risk of preterm labor (relative risk (RR) = 1.35 [1.11, 1.63]), low birth weight (RR = 1.52 [1.24, 1.87]) and perinatal mortality (RR = 1.84 [1.15, 2.94]). No evidence of increased risk was associated with Chlamydia infection in regard to premature rupture of membranes (RR = 1.13 [0.95, 1.34]), abortion and postpartum endometritis (RR = 1.20 [0.65, 2.20] and 0.89 [0.49, 1.61] respectively).

CONCLUSION:

The diagnosis and treatment of Chlamydia cervicitis during pregnancy can reduce perinatal morbidity and mortality associated with this infection. However, clinical trials are needed to confirm these findings.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Complicações Infecciosas na Gravidez / Infecções por Chlamydia / Cervicite Uterina / Mortalidade Perinatal Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Risk_factors_studies / Systematic_reviews Limite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Braz. j. infect. dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2011 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Complicações Infecciosas na Gravidez / Infecções por Chlamydia / Cervicite Uterina / Mortalidade Perinatal Tipo de estudo: Diagnostic_studies / Etiology_studies / Guideline / Risk_factors_studies / Systematic_reviews Limite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Braz. j. infect. dis Assunto da revista: DOENCAS TRANSMISSIVEIS Ano de publicação: 2011 Tipo de documento: Article / Project document País de afiliação: Brasil País de publicação: Brasil