Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant
Rev. bras. hematol. hemoter
; Rev. bras. hematol. hemoter;33(5): 383-388, Oct. 2011. tab
Article
em En
| LILACS
| ID: lil-606716
Biblioteca responsável:
BR408.1
ABSTRACT
The Epstein-Barr virus is responsible for infectious mononucleosis syndrome and is also closely associated to several types of cancer. The main complication involving Epstein-Barr virus infection, both in recipients of hematopoietic stem cells and solid organs, is post-transplant lymphoproliferative disease. The importance of this disease has increased interest in the development of laboratory tools to improve post-transplant monitoring and to detect the disease before clinical evolution. Viral load analysis for Epstein-Barr virus through real-time polymerase chain reaction is, at present, the best tool to measure viral load. However, there is not a consensus on which sample type is the best for the test and what is its predictive value for therapeutic interventions.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Reação em Cadeia da Polimerase
/
Transtornos Linfoproliferativos
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Rev. bras. hematol. hemoter
Assunto da revista:
HEMATOLOGIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil