Effectiveness of confidential unit exclusion in screening blood donors of the regional blood bank in Londrina, Paraná State
Rev. bras. hematol. hemoter
; Rev. bras. hematol. hemoter;33(5): 347-352, Oct. 2011. tab
Article
em En
| LILACS
| ID: lil-606710
Biblioteca responsável:
BR408.1
ABSTRACT
BACKGROUND:
For transfusion purposes, blood donors must be accepted both in clinical and serological evaluations and must not have excluded their own donation using the confidential unit exclusion.AIMS:
The objective of this study was to verify whether blood donors who choose self exclusion are more likely to be positive in serological tests than donors who do not.METHODS:
A cross-sectional analysis was carried out of 51,861 consecutive whole blood donations from January 2004 to December 2008 at a public blood bank in Londrina, Southern Brazil.RESULTS:
Self exclusion was chosen in 1672 (3.2 percent) donations, most frequently by first-time blood donors (p-value < 0.0001), by blood donors from external collections (p-value < 0.0001), by men (p value < 0.0001) and by under 30-year-old donors (p-value < 0.0001). The frequency of positive serology was 5.3 percent in the group that chose self exclusion and 3.5 percent in the group that did not choose self exclusion (p-value < 0.0001).CONCLUSIONS:
These results show that confidential unit exclusion used in this blood bank is effective and is inexpensive. However, the diagnostic power to detect blood-borne infections was low and resulted in the discard of a high number of blood bags without any direct or indirect serologic markers of pathogens. The use of confidential unit exclusion could be replaced with molecular tests to screen blood donors.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Doadores de Sangue
/
Transfusão de Sangue
/
Testes Sorológicos
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Rev. bras. hematol. hemoter
Assunto da revista:
HEMATOLOGIA
Ano de publicação:
2011
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil